I made an account just to comment on this, in fact. As a nonbinary trans person the comic with the Johnbie presenting a piece of paper mocking nonbinary and gender-nonconforming people made me really, really dysphoric.
As a trans person this comic kiiiiiiiiinda sucks. Yes, gender roles are fed to us on a daily basis and are really terrible but the image of pills feels like an attack especially since HRT often comes in pill form...